Figure 3.

Irreversible blockage of 5HT (10⁻⁸ M) currents by EEDQ in oocytes expressing 5HT2c receptors. 5HT2c receptor mediated oscillatory currents were measured in control oocytes and in oocytes pretreated with EEDQ (2 × 10⁻⁴ M, for 75 min). The EEDQ-treated oocytes were washed for 1–4 h, or for more than 24 h, in Ringer’s solution before recording. Results are mean ± SD (n = 4 oocytes). Recordings were made 6 and 7 days after cRNA injection.