Table 1 Baseline characteristics.
Men (n = 34 020) | Women (n = 19 761) | Unadjusted OR (95% CI) | Age‐adjusted OR* (95% CI) | |
---|---|---|---|---|
Age, mean (SD),years | 69 (12) | 73 (11) | – | – |
Risk factors | ||||
Hypertension | 35 | 43 | 0.71 (0.69–0.74) | 0.74 (0.71–0.77) |
Diabetes | 21 | 24 | 0.84 (0.80–0.87) | 0.86 (0.82–0.89) |
Current smoker | 21 | 17 | 1.28 (1.22–1.34) | 0.96 (0.91–1.01) |
History of MI | 36 | 30 | 1.27 (1.23–1.32) | 1.44 (1.38–1.49) |
History of PCI | 9 | 6 | 1.56 (1.45–1.68) | 1.35 (1.26–1.45) |
History of CABG | 9 | 5 | 1.97 (1.83–2.13) | 1.94 (1.79–2.09) |
Medical treatment before admission | ||||
ACE inhibitor | 21 | 21 | 0.99 (0.94–1.03) | 1.03 (0.99–1.08) |
Aspirin/other thrombocyte inhibitor | 53 | 52 | 1.04 (1.01–1.08) | 1.15 (1.11–1.20) |
Oral anticoagulant | 6 | 5 | 1.21 (1.12–1.31) | 1.36 (1.25–1.47) |
β‐blocker | 46 | 47 | 0.95 (0.92–0.98) | 0.97 (0.93–1.00) |
Digitalis | 7 | 10 | 0.69 (0.64–0.73) | 0.89 (0.83–0.95) |
Diuretic | 26 | 41 | 0.50 (0.49–0.52) | 0.63 (0.60–0.65) |
Long‐acting nitroglycerine | 29 | 31 | 0.88 (0.85–0.92) | 1.04 (0.99–1.08) |
Lipid‐lowering therapy | 22 | 19 | 1.23 (1.18–1.29) | 1.06 (1.01–1.11) |
Medical history | ||||
Stroke | 12 | 12 | 1.02 (0.97–1.08) | 1.27 (1.20–1.35) |
Renal failure | 1.9 | 1.3 | 1.44 (1.25–1.66) | 1.56 (1.35–1.80) |
COPD | 6 | 7 | 0.78 (0.72–0.83) | 0.86 (0.80–0.93) |
Dementia | 0.2 | 0.4 | 0.52 (0.38–0.71) | 0.68 (0.50–0.93) |
Heart failure | 13 | 17 | 0.72 (0.68–0.75) | 0.93 (0.88–0.98) |
Cancer diagnosed last 3 years | 4.8 | 3.8 | 1.26 (1.15–1.37) | 1.50 (1.37–1.64) |
Ischaemic signs | ||||
ST depression† | 34 | 38 | 0.83 (0.80–0.86) | 0.95 (0.92–0.99) |
Marker elevation (n = 47 348)§ | ||||
CKMB⩾5 μg/l / TnT⩾0.06 μg/l | 79 | 79 | 1.02 (0.99–1.06) | 1.16 (1.11–1.21) |
CKMB⩾10 μg/l / TnT⩾0.1 μg/l | 72 | 71 | 1.05 (1.01–1.09) | 1.20 (1.15–1.25) |
Diagnosis at discharge | ||||
NSTEMI | 72 | 73 | 0.91 (0.88–0.95) | 1.09 (1.05–1.14) |
UAP | 29 | 27 | 1.10 (1.05–1.14) | 0.92 (0.88–0.96) |
Data are presented as percentages unless otherwise indicated.
CABG, coronary artery bypass grafting; CKMB, creatine kinase muscle/brain; COPD, chronic obstructive pulmonary disease; MI, myocardial infarction; PCI, percutaneous coronary intervention; NSTEMI, non‐ST‐elevation myocardial infarction; TnT, troponin T; UAP, unstable angina pectoris.
*Odds ratios were obtained by logistic regression analysis and presented for men vs women.
†ST‐segment depression was defined as ⩾1 mm depression of the ST‐segment in ⩾2 leads, on admission ECG.
§Valid values for CKMB or TnT were available in 88% of the cases. Different troponin I methods or CKB were used otherwise.