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. 2007 Feb 16;93(11):1398–1405. doi: 10.1136/hrt.2006.106955

Table 2 Number of patients with CHD with appropriate assessment and treatment with specified drugs for secondary prevention at baseline and after 1 year of follow‐up.

Number of observations Number (%) Estimated intra‐cluster correlation coefficients* (SE) OR (95% CI)* p Value
Intervention Control
Risk factors
BP measured
 Baseline 1012 363 (81.8) 460 (81.0)
 Follow‐up 1058 446 (99.1) 514 (84.5) 0.1259 (0.0476) 22.61 (6.47 to 70.13) <0.0001
Cholesterol measured
 Baseline 892 228 (51.8) 350 (77.4)
 Follow‐up 1059 333 (74.0) 403 (66.2) 0.1271 (0.0487) 1.21 (0.71 to 2.08) 0.4813
Smoking status recorded
 Baseline 1045 168 (38.0) 197 (32.7)
 Follow‐up 1059 421 (93.6) 273 (44.8) 0.0773 (0.0333) 33.96 (14.49 to 79.62) <0.0001
BMI measured or weight checked
 Baseline 1059 189 (42.2) 220 (36.0)
 Follow‐up 1059 396 (88.2) 281 (46.1) 0.0125 (0.0412) 10.14 (4.99 to 20.55) <0.0001
Risk factor management
BP<140/85 mm Hg
 Baseline 1004 184 (43.1) 246 (42.6)
 Follow‐up 962 250 (56.1) 223 (43.2) 0.0002 (0.0034) 1.61 (1.22 to 2.13) 0.0113
Cholesterol<5 mmol/l
 Baseline 785 202 (60.5) 255 (56.5)
 Follow‐up 735 249 (74.3) 254 (63.5) 0.1115 (0.0214) 1.58 (1.05 to 2.37) 0.0314
Prescribing of secondary prevention medicines
Lipid‐lowering medication
 Baseline 1080 230 (49.9) 280 (45.2)
 Follow‐up 1080 275 (59.6) 322 (52.0) 0.0051 (0.0079) 1.99 (1.06 to 3.74) 0.0281
Aspirin
 Baseline 1080 300 (65.1) 388 (62.7)
 Follow‐up 1080 314 (68.1) 411 (66.4) 0.0021 (0.0165) 1.08 (0.84 to 1.40) 0.5502
Beta‐blocker†
 Baseline 586 110 (44.2) 122 (36.2)
 Follow‐up 586 125 (50.2) 141 (41.8) 0.0001 (0.0024) 1.43 (1.19 to 1.99) 0.0354
ACE inhibitor†
 Baseline 489 84 (39.4) 117 (42.4)
 Follow‐up 489 103 (48.4) 140 (50.7) 0.0179 (0.0194) 0.97 (0.68 to 1.43) 0.9301

Values are numbers (percentages) unless stated otherwise.

BMI, body mass index; BP, blood pressure.

*Values adjusted for baseline, age, gender and practice. †Patients with past history of myocardial infarction only.