Table 1.

Morphometric Measurements

	WT	HET	HOM
Heart Weight/Body Weight (mg/g)
Baseline	4.11±0.10	4.15±0.12	4.48±0.13^†
Postpartum	3.52±0.19	5.66±0.38^*^†	6.19±0.46^*^†
21 days post TAC	7.40±0.38^*^#	8.77±0.41^*^†^#	9.59±0.59^*^†^#

Heart Weight/Tibia Length (mg/mm)
Baseline	6.54±0.19	7.32±0.16^†	8.15±0.22^†^‡
Postpartum	7.38±0.20^*	8.76±0.38^*^†	10.18±0.62^*^†
21 days post TAC	10.79±0.43^*^#	12.05±0.41^*^†^#	13.04±0.59^*^†^#

Lung Weight/Tibia Length (mg/mm)
Baseline	8.28±0.26	9.62±0.20^†	9.54±0.18^†
Postpartum	9.55±0.32^*	9.80±0.41	10.71±0.31^*^†
21 days post TAC	13.14±1.60^*^#	21.85±1.46^*^†^#	20.90 ±1.54^*^†^#

= P < 0.05 to baseline mice

^†

= P < 0.05 to WT mice of same group

^‡

= P < 0.05 to HET mice of same group

= P < 0.05 to postpartum mice

n=30, 23 & 30 for WT, HET & HOM baseline mice

n=19, 8 & 9 for WT, HET & HOM postpartum mice

n=13, 17 & 16 for WT, HET & HOM TAC mice