Table 2.

Left Ventricular Chamber Dimensions and Function from Echocardiography

	WT	HET	HOM
Posterior Wall Thickness (mm)
Baseline	0.68±0.02	0.67±0.03	0.67±0.02
Postpartum	0.67±0.01	---	0.68±0.02
21 days post TAC	0.83±0.03*#	0.78±0.03*	0.88±0.04*#
Ventricular Septal Thickness (mm)
Baseline	0.61±0.01	0.67±0.03	0.65±0.02
Postpartum	0.62±0.01	---	0.66±0.02
21 days post TAC	0.76±0.03*#	0.76±0.02*	0.83±0.04*#
End Diastolic Dimension (mm)
Baseline	3.57±0.09	3.64±0.08	3.95±0.10†‡
Postpartum	4.14±0.11*	---	4.52±0.09*†
21 days post TAC	3.98±0.11*	4.64±0.12*†	4.76±0.17*†
End Systolic Dimension (mm)
Baseline	2.30±0.13	2.46±0.09	2.83±0.09†‡
Postpartum	2.95±0.10*	---	3.39±0.08*†
21 days post TAC	2.81±0.16*	3.74±0.15*†	4.10±0.13*†#
Left Ventricular Mass (mg)
Baseline	74±4	80±6	91± 3†
Postpartum	95±6*	---	117± 6*†
21 days post TAC	118±7*#	145±8*†	178±17*†#
Left Ventricular Fractional Shortening (%)
Baseline	36.0±2.9	32.5±1.1	28.3±1.3†‡
Postpartum	28.9±1.5	---	24.2±1.2*†
21 days post TAC	30.1±2.5	19.9±1.8*†	12.7±1.0*†‡#
Velocity of Circumferential Fiber Shortening (mm/ms)
Baseline	6.28±0.43	5.73±0.27	5.30±0.28
Postpartum	5.79±0.47	---	4.76±0.24†
21 days post TAC	5.80±0.49	3.80±0.35*†	2.97±0.30*†#

^*= P < 0.05 to baseline mice

^†= P < 0.05 to WT mice of the same group

^‡= P < 0.05 to HET mice of the same group

^#= P < 0.05 to Postpartum mice

^---= no data available for PP HET.

n=15, 16 & 17 for WT, HET & HOM baseline mice

n=12 & 23 for WT & HOM postpartum mice

n=15, 16 & 17 for WT, HET & HOM TAC mice