Table 2.
Serum Antibody Responses to Inactivated Influenza Vaccine With or Without QS21 Adjuvant
| Hemagglutination Inhibition | Neutralization | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| GMT (log2)1 | % Rise2 | GMT (log2)1 | % Rise2 | ||||||
| Antigen | Day | Aq | QS21 | Aq | QS21 | Aq | QS21 | Aq | QS21 |
| A/Panama (H3N2) | 0 | 3.4 | 3.6 | 5.0 | 4.6 | ||||
| 14 | 7.1 | 6.1 | 10.1 | 9.4 | |||||
| 28 | 6.1 | 6.1 | 87 | 79 | 9.9 | 9.2 | 93 | 93 | |
| A/New Caledonia (H1N1) | 0 | 2.4 | 2.4 | 2.1 | 2.3 | ||||
| 14 | 5.8 | 5.5 | 6.9 | 7.3 | |||||
| 28 | 5.3 | 5.1 | 73 | 79 | 7.3 | 6.6 | 87 | 100 | |
| B/Yamanashi | 0 | 3.2 | 3.7 | 3.4 | 3.7 | ||||
| 14 | 4.9 | 6.3 | 7.2 | 8.2 | |||||
| 28 | 4.9 | 5.4 | 80 | 79 | 7.4 | 7.8 | 93 | 93 | |
1
Geometric mean titer
2
≥4-fold