Table 2.
Tissue | Wild type | MBD-deficient | Wild-type activity†, % |
---|---|---|---|
Lung | 247.5* | 86.6 | 35 |
Kidney | 179.6 | 28.6 | 16 |
Small intestine | 101.2 | 87.2 | 86 |
Heart | 39.4 | 12.1 | 31 |
Liver | 32.8 | 26.4 | 81 |
Pancreas | 8.5 | 3.1 | 37 |
Assays were performed in duplicate by using tissue homogenates from male mice. For each determination, three mice were used. For calculation of specific activity, values from the initial portion of the curve where the activity was most linear were used. Each SEM was 10-20% of the averaged values.
nmol LTE4 formed/mg protein per h.
MBD-deficient specific activity/Wild-type specific activity × 100.