Table 2.

The variation in effects seen with different Cdc18 constructs

Construct	Effects
	Re-replication	Mitotic block	Rad3-dependent block	Transient block	Changes in size/variability chromosome III
pRep3X cdc18	Yes	Yes	No	No	Not known
(Nishitani and Nurse, 1995)
pRep3X C-terminus cdc18	Yes	Yes	Yes	No	Not known
(Greenwood et al., 1998)
pRep3X N-terminus cdc18	No	Yes	No	No	Not known
(Greenwood et al., 1998)
pRep4X cdc18	No	Yes	Yes	No	Not known
(This article)
cdc18-T6A	No	Yes	Yes	Yes	Yes
(This article)