Table 1.
Analysis of the slippery sequence from different viral frameshift regions
| Virus | Extended version of slippery sequences |
|---|---|
| Human immunodeficiency virus type 1 | G GCU AAU UUU UUA |
| Simian immunodeficiency virus | G GCA AAU UUU UUA |
| Human immunodeficiency virus type 2 | G GCA GGU UUU UUA |
| Rous sarcoma virus | C UUG ACA AAU UUA |
| Saccharomyces cerevisiae virus L-A | U CAG CAG GGU UUA |
| Giardia virus | C GCC AUC CCU UUA |
| Gill-associated virus | G AGG CAA AUU UUC |
| Human T-cell lymphotropic virus type 2 (gag/pro) | C UGA GGA AAA AAC |
| Bovine leukaemia virus (gag/pro) | C AAA UCA AAA AAC |
| Mouse mammary tumour virus (gag/pro) | A AAU UCA AAA AAC |
| Equine infectious anaemia virus | U GUU CCA AAA AAC |
| Human T-cell lymphotropic virus type 1 (gag/pro) | A CAC CCA AAA AAC |
| Simian T-cell lymphotropic virus type 1 (gag/pro) | A CAC CCA AAA AAC |
| Human astrovirus | G GCC CCA AAA AAC |
| Porcine reproductive and respiratory syndrome virus | G CAG UGU UUA AAC |
| Berne virus | G GGU GAU UUA AAC |
| Subterranean clover mottle virus | C GAG CAU UUA AAC |
| Avian infectious bronchitis virus | G AAU UAU UUA AAC |
| Human coronavirus | C AGU UAU UUA AAC |
| Murine hepatitis virus | G AAC UUU UUA AAC |
| Severe acute respiratory syndrome coronavirus | A ACG UUU UUA AAC |
| Human T-cell lymphotropic virus type 1 | G UUC CCU UUA AAC |
| Simian T-cell lymphotropic virus type 1 | G UUC CCU UUA AAC |
| Bovine leukaemia virus | A UUC CCU UUA AAC |
| Human T-cell lymphotropic virus type 2 | A UUU CCU UUA AAC |
| Cocksfoot mottle virus | C CGG CCU UUA AAC |
| Potato leafroll virus | C AAG CCU UUA AAU |
| Mason–Pfizer monkey virus (gag/pro) | A UUU CAG GGA AAC |
| Simian type D virus 1 (gag/pro) | C CAU CAG GGA AAC |
| Simian retrovirus type 2 (gag/pro) | C CAU CAG GGA AAC |
| Visna virus (gag/pro) | C CAU CAG GGA AAC |
| Feline immunodeficiency virus | G AAU UCG GGA AAC |
| Beet western yellow virus | U CUG UCG GGA AAC |
| Cereal yellow dwarf virus | C GAG UCG GGA AAC |
| Cucurbit aphid-borne yellows virus | C GAG UCG GGA AAC |
| Mason–Pfizer monkey virus | C CAU GGA AAU UUU |
| Simian type D virus 1 | A UUU GGA AAU UUU |
| Simian retrovirus type 2 | A UUU GGA AAU UUU |
| Visna virus | U UUU GGA AAU UUU |
| Barley yellow dwarf virus | C UCU GUG GGU UUU |
| Peaenation mosaic virus RNA 2 | C GCG GCG GAU UUU |
The extended slippery sequence from eukaryotic viruses, A BCX XXY YYZ, is indicated in bold (where the spaces correspond to the initial reading frame). The sequences were retrieved from the RECODE database (51). The nucleotides at position A BC are in italics. The slippery sequences used in this study are underlined. Frameshift regions are located at the viral gag/pol junction except when specified otherwise (gag-pro).