Table 1.
P-values for Student's; t- and F-tests comparing alternative acceptors against constitutive/pseudo acceptors based for the following features: distal splice sites (Dist SS), proximal splice sites (Prox SS), average intronic conservation in 100 nt upstream of the proximal splice site (IC100), PPT length, PPT score, distance of PPT to the distal site (PPT∼D) and the proximal site (PPT∼P), ESE/ESS density, pseudo HAG sites and GC content
Feature | NAGNAG-P | NAGNAG-D | CLOSE | MID | FAR | |||||
---|---|---|---|---|---|---|---|---|---|---|
t P-val | F P-val | t P-val | F P-val | t P-val | F P-val | t P-val | F P-val | t P-val | F P-val | |
Dist SS | 2.E−16 | 0.215 | 1.E−09 | 2.E−16 | 0.371 | 0.183 | 0.321 | 0.005 | 0.003 | 0.049 |
Prox SS | 2.E−06 | 1.E−07 | 0.236 | 0.026 | 0.730 | 0.241 | 0.083 | 0.169 | 0.063 | 0.260 |
IC100 | 4.E−04 | 0.144 | 0.007 | 0.037 | 0.013 | 0.435 | 2.E−10 | 0.373 | 3.E−06 | 0.465 |
PPT Length | 0.226 | 0.344 | 0.996 | 0.030 | 0.823 | 0.004 | 0.001 | 2.E−14 | 0.061 | 2.E−10 |
PPT Score | 0.525 | 0.748 | 0.211 | 0.199 | 0.012 | 6.E−13 | 4.E−08 | 8.E−07 | 3.E−07 | 3.E−10 |
PPT∼D | 0.054 | 0.233 | 0.901 | 0.516 | 5.E−09 | 0.002 | 0.854 | 0.038 | 1.E−05 | 0.161 |
PPT∼P | na | na | na | na | 1.E−06 | 0.007 | 0.986 | 0.055 | 0.023 | 0.001 |
BP score | 0.525 | 0.748 | 0.2388 | 0.2338 | 0.289 | 0.539 | 0.4418 | 0.239 | 0.4564 | 0.550 |
BP∼D | 0.054 | 0.233 | 0.6724 | 0.9282 | 8.88E−07 | 0.017 | 0.002 | 0.154 | 1.30E−05 | 0.021 |
BP∼P | na | na | na | na | 2.90E−04 | 0.031 | 1.22E−04 | 0.143 | 0.005 | 2.85E−04 |
ESE | 0.042 | 0.020 | 0.850 | 0.812 | 0.708 | 0.618 | 0.031 | 0.331 | 0.042 | 0.020 |
ESS.hex2 | 0.873 | 0.252 | 0.582 | 0.948 | 0.721 | 0.186 | 0.064 | 0.157 | 0.176 | 0.135 |
ESS.hex3 | 0.350 | 0.023 | 0.710 | 0.779 | 0.985 | 0.170 | 0.606 | 0.112 | 0.324 | 0.428 |
HAG | 0.888 | 0.561 | 0.601 | 0.023 | 0.023 | 0.723 | 2.E−04 | 0.490 | 1.E−04 | 0.868 |
GC | 0.265 | 0.512 | 1.E−04 | 0.714 | 2.E−04 | 0.711 | 0.044 | 0.999 | 0.149 | 0.312 |
Results are shown for the different datasets: FAR, MID, CLOSE, NAGNAG-proximal and NAGNAG-distal. Significant values (based on Westfall–Young correction) are indicated in bold.