Figure 4.

Subjects grouped with different CD4 cell counts mounted a different magnitude and breadth of CTL responses targeting Gag. For each portion of the HIV-1 proteins (Gag, p17, p24 or p15), the total magnitude or breadth of each individual is dotted and the median values are shown as a dash. Black dots are responses targeting consensus clade B peptides and blue dots for responses targeting clade C peptides. The filled dots designate the values from the group of CD4 cell counts less than 200/μl, the circles for individuals with CD4 cell counts ranging from 200–400/μl and the triangles for CD4 cell counts more than 400/μl. The p values were obtained using One Way Analysis of Variance (ANOVA) for multiple group comparison and Dunn's method or Holm-Sidak method for pair wise multiple comparison, when appropriate for data distribution.