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Effect of modification of U7.3 RNA on correction of splicing. Lanes: 1, untreated IVS2–705 cells; 2–4, U7SmOPT; 5–7, U7.3; 8–10, U7.324; 11–13, U7.34. See Fig. 1C for sequences of the constructs. Lane 14, RNA from human blood. All other designations are as described in the legend to Fig. 2.
