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. 2007 Sep 3;8:329. doi: 10.1186/1471-2105-8-329

Table 4.

Example with BCL2_HUMAN

Ranking Symbol UniProt χ2 Common terms Pfam Organism Local alignment
hit size Identity %
1 BCL2_HUMAN P10415 20080,7 62 Bcl-2 Homo sapiens 239 100.0
2 Bcl2 P49950 19405,8 61 Bcl-2 Rattus norvegicus 239 89.1
3 BCLX_HUMAN Q07817 13329,9 44 Bcl-2 Homo sapiens 238 45.0
4 Becn1 Q91XJ1 10944,1 43 APG6 Rattus norvegicus 108 23.1
5 BNIP3_HUMAN Q12983 10529 39 BNIP3 Homo sapiens 263 18.3
6 Bcl2l1 P53563 10426,8 45 Bcl-2 Rattus norvegicus 238 44.5
7 ATBI-1 Q9LD45 10199,5 34 UPF0005 Arabidopsis thaliana 152 18.4
8 API5_PONPY Q5R644 10015,8 34 API5 Pongo pygmaeus 80 25.0
9 Q7ZY79_XENLA Q7ZY79 10015,8 34 API5 Xenopus laevis 36 30.6
10 Mcl1 Q9Z1P3 9987,1 42 Bcl-2 Rattus norvegicus 185 30.3
11 MCL1_HUMAN Q07820 9987,1 42 Bcl-2 Homo sapiens 265 23.4
12 AIF1_HUMAN P55008 9494,6 37 - Homo sapiens 33 30.3
13 O60667 O60667 9365,6 32 - Homo sapiens 50 38.0
14 BI1_HUMAN P55061 9345,2 34 UPF0005 Homo sapiens 155 19.4
15 Ets1 P41156 9302,5 42 Ets Rattus norvegicus 53 28.3
16 API5_CHICK Q5ZMW3 9245,1 34 API5 Gallus gallus 107 23.4
17 Bcl2l2 P70345 9232,3 30 Bcl-2 Mus musculus 235 37.0
18 Bnip1 Q8VHI8 9206,8 29 Sec20 Rattus norvegicus 25 32.0
19 BNIP1_HUMAN Q12981 9206,8 29 Sec20 Homo sapiens 13 38.5
20 Son_predicted Q6PDU3 9160,2 33 - Rattus norvegicus
21 BNIPL_HUMAN Q7Z465 9114,8 33 - Homo sapiens 73 23.3
22 BCL2_BOVIN O02718 9109,8 29 Bcl-2 Bos taurus 239 90.4
23 BCL2_CHICK Q00709 9109,8 29 Bcl-2 Gallus gallus 246 74.4
24 BCL2_CRIGR Q9JJV8 9109,8 29 Bcl-2 Cricetulus griseus 239 89.1
25 Api5 O35841 9083,1 32 API5 Mus musculus 80 25.0
26 Il1a P16598 9080,0 43 IL1 Rattus norvegicus 92 21.7
27 IL1A_HUMAN P01583 9077,8 43 IL1 Homo sapiens 42 26.2
28 Q9HD91 Q07820 9060,0 39 Bcl-2 Homo sapiens 265 23.4
29 Q9UNJ1 Q07820 9060,0 39 Bcl-2 Homo sapiens 265 23.4
30 Q8HYS5_CANFA Q8HYS5 9060,0 39 Bcl-2 Canis familiaris 215 28.4

The table contains the following information: The ranking of the potential functional analogues of BCL2_HUMAN according the χ2 – value, the gene name and the UniProt accession number, the χ2 – value, the number of common terms between a hit and BCL2_HUMAN, the Pfam name with short domain description the gene product belongs to, the organism the gene products is from, and the local alignment characteristics, such as hit length and the % identity of the hit, of the alignment between BCL2_HUMAN and the hit sequence.