Table 3. Measurement of Serum Lipid and Leptin Levels.
No. of pools | Diet | total | leptin | |||
---|---|---|---|---|---|---|
XOL mg/dl |
HDL mg/dl |
glucose mg/dl |
ng/ml |
|||
Lean | 14 | chow | 68.9±2.3a | 68.2±2.3a | 206.7±10.1a | 3.0±0.6a |
Het-Ob | 13 | chow | 62.8±4.1a | 63.6±3.8a | 116.4±9.4b | 1.7±0.3b |
Homo-Ob | 11 | chow | 146.7±4.9b | 143.2±9.1b | 428.0±23.3c | 0.4±0.03b |
Lean | 10 | xol | 88.8±10.7c | 70.3±5.8c | 221.1±8.1d | 4.9±0.5*c |
Het-Ob | 10 | xol | 139.5±3.0*d | 97.7±2.1*d | 200.1±20.8*d | 2.7±0.4d |
Homo-Ob | 8 | xol | 221.5±14.6*e | 192.0±9.7*e | 395.1±18.9*e | 0.6±0.05e |
Two Way ANOVA p-value | ||||||
Strain Effects | <0.001 | <0.001 | <0.001 | <0.001 | ||
Diet Effects | <0.001 | <0.001 | 0.025 | 0.015 | ||
Strain-Diet Interaction | <0.001 | <0.001 | <0.001 | 0.295 |
NOTE: Data represent mean ±SEM.
Different superscript letters among strains on same diet indicate significant difference from one another, p < 0.001. *p < 0.05 vs same strain on chow diet.
Abbreviations: XOL = Cholesterol, HDL = High Density Lipoprotein