Table V. Univariate analysis of risk factors for overall morbidity after hepatic resection.
Variable | No. of patients with complications | Percentage (%) | p value | |
---|---|---|---|---|
Age (years) | >50 | 64/119 | 53.8 | 0.007* |
<50 | 44/122 | 27.9 | ||
Gender | Male | 64/144 | 44.4 | 0.896 |
Female | 44/97 | 45.4 | ||
Diagnosis | Benign | 22/84 | 26.2 | <0.001* |
Malignant | 86/157 | 54.8 | ||
Comorbid medical conditions | No | 60/164 | 36.6 | <0.001* |
Yes | 48/77 | 62.3 | ||
Clinical jaundice | No | 74/189 | 39.1 | 0.001* |
Yes | 34/52 | 65.4 | ||
Preoperative serum bilirubin (>10 mg) | No | 92/216 | 42.6 | 0.055 |
Yes | 16/25 | 64 | ||
Preoperative serum creatinine (>1.3 mg/dl) | No | 98/229 | 42.8 | 0.007* |
Yes | 10/12 | 83.3 | ||
Preoperative serum albumin | Normal (>3.5 g/dl | 68/172 | 39.5 | 0.010 |
Subnormal (<3.5 g/dl) | 40/69 | 58 | ||
Preoperative platelet count | >150 000 | 96/217 | 44.2 | 0.667 |
<150 000 | 12/24 | 50 | ||
Prothrombin time | Normal | 95/219 | 43.3 | 0.181 |
Deranged | 13/22 | 59.1 | ||
HBsAg status | No | 83/200 | 41.5 | 0.006* |
Yes | 12/15 | 80 | ||
Extent of hepatic resection | Minor (≤2 segments) | 52/130 | 40 | 0.119 |
Major (>2 segments) | 56/111 | 50.5 | ||
Complex hepatectomy | No | 62/155 | 40 | 0.058 |
Yes | 46/86 | 53.5 | ||
Bile duct excision | No | 76/181 | 42 | 0.136 |
Yes | 32/60 | 53.3 | ||
Elective/emergency | Elective | 99/229 | 43.2 | 0.038* |
Emergency | 9/12 | 75 | ||
Liver cancer with cirrhosis | No | 94/226 | 41.6 | <0.001* |
Yes | 14/15 | 93.3 | ||
Gall bladder cancer with jaundice | No | 88/213 | 41.3 | 0.004* |
Yes | 20/28 | 71.4 | ||
Pringle manoeuvre | No | 55/138 | 51.5 | 0.089 |
Yes | 53/103 | 39.9 | ||
Intraoperative blood transfusion | No | 8/36 | 22.2 | 0.003* |
Yes | 100/205 | 48.8 | ||
Intraoperative blood transfusion (units) | <3 units | 46/141 | 32.6 | <0.001* |
>3 units | 62/100 | 62 | ||
Techniques of resection | Kellyclysis | 59/139 | 42.8 | 0.513 |
CUSA | 49/102 | 47.6 | ||
Duration of surgery | >180 min | 97/200 | 43.9 | 0.015* |
<180 min | 11/41 | 26.8 | ||
Liver pathology | Non-cirrhotic | 91/221 | 41.2 | <0.001* |
Cirrhotic | 17/20 | 85 | ||
Year 1996–2000 | 36/66 | 54.5 | 0.081 | |
Year 2001–2005 | 72/175 | 41.1 |
*Significant p value.