Table 2.
Relative risk of thrombosis for hemostatic factors comparing the Leiden Thrombophilia Study (LETS) and the Longitudinal Investigation of Thromboembolism Etiology (LITE)
| Risk Factor | LETS | LITE |
|---|---|---|
| Factor V Leiden | 8.1 | 3.5 |
| Factor V Leiden homozygote | 80 | 24 |
| Prothrombin 20210A | 2.8 | 1.9 |
| Protein C deficiency | 3.1 | 3.4 |
| Elevated factor V | 1.3 | 1.2 |
| Antithrombin deficiency | 5.0 | Not done |
| Elevated factor VIII | 4.8 | 2.6 |
| Elevated factor VII | 0.8 | 2.4 |
| Elevated factor IX | 2.8 | Not done |
| Elevated factor XI | 2.2 | Not done |
| Elevated fibrinogen | 4.0 | 0.9 |
| Elevated D-dimer | 2.5 | 3.1 |
| Elevated homocysteine | 2.5 | 1.5 |