Table 4.
Hazard ratios (HRs)* of endpoints in relation to categories of DASH Diet Index Score, IWHS
| Categories of DASH Diet Index Score
|
||||||
|---|---|---|---|---|---|---|
| 0.5–3.5 | 4.0–4.0 | 4.5–5.0 | 5.5–6.0 | 6.5–10.0 | p for trend | |
| N at risk† | 5017 | 2543 | 5100 | 4292 | 4041 | |
| Incident Hypertension | ||||||
| Person years | 43542 | 22528 | 45150 | 37551 | 36289 | |
| n of events | 978 | 466 | 977 | 858 | 731 | |
| HR1 (95% CI) | 1.0 | 0.91 (0.81–1.02) | 0.95 (0.87–1.04) | 0.99 (0.90–1.09) | 0.87 (0.79–0.96) | 0.02 |
| HR2 (95% CI) | 1.0 | 0.94 (0.84–1.05) | 0.99 (0.91–1.08) | 1.06 (0.97–1.17) | 0.97 (0.87–1.07) | 0.96 |
| CHD death | ||||||
| Person years | 70445 | 35945 | 72155 | 60626 | 57560 | |
| n of events | 155 | 65 | 154 | 146 | 100 | |
| HR1 (95% CI) | 1.0 | 0.77 (0.58–1.04) | 0.89 (0.71–1.11) | 0.96 (0.77–1.20) | 0.67 (0.52–0.86) | 0.01 |
| HR2 (95% CI) | 1.0 | 0.85 (0.64–1.14) | 1.02 (0.81–1.27) | 1.14 (0.91–1.44) | 0.86 (0.67–1.12) | 0.69 |
| Stroke death | ||||||
| n of events | 60 | 29 | 50 | 52 | 45 | |
| HR1 (95% CI) | 1.0 | 0.88 (0.57–1.37) | 0.74 (0.51–1.07) | 0.86 (0.60–1.25) | 0.76 (0.51–1.12) | 0.22 |
| HR2 (95% CI) | 1.0 | 0.91 (0.58–1.41) | 0.76 (0.52–1.11) | 0.91 (0.62–1.33) | 0.82 (0.55–1.23) | 0.44 |
| All CVD death | ||||||
| n of events | 273 | 122 | 273 | 254 | 199 | |
| HR1 (95% CI) | 1.0 | 0.82 (0.67–1.02) | 0.89 (0.75–1.06) | 0.94 (0.80–1.12) | 0.75 (0.63–0.90) | 0.01 |
| HR2 (95% CI) | 1.0 | 0.89 (0.72–1.10) | 0.99 (0.84–1.18) | 1.09 (0.91–1.29) | 0.93 (0.76–1.12) | 0.85 |
CHD = coronary heart disease CVD = cardiovascular disease
HR1 is the hazard ratio per quintile of DASH score, relative to the first quintile, adjusted for age (continuous) and energy intake (continuous). HR2 is further adjusted for education (<high school, high school, >high school), BMI (continuous), waist/hip (continuous), smoking status (current, former, never) and pack-years (continuous), estrogen use (current, former, never), alcohol intake (0, <4, ≥4 g/d), physical activity (low, medium, high), and multivitamin use (yes, no, unknown).
Follow-up was from 1986 through 1997 for hypertension and through 2002 for deaths.