TABLE 2.
Six Sigma Gene Changes for 1,6 BPQ sorted according to FOLD
| Probe | Gene | Description | FOLD 1,6-BPQ |
|---|---|---|---|
| 203665_at | HMOX1 | heme oxygenase (decycling) 1 | 16.5 |
| 209921_at | SLC7A11 | solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 | 7.6 |
| 206561_s_at | AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 6.3 |
| 201467_s_at | NQO1 | NAD(P)H dehydrogenase, quinone 1 | 5.8 |
| 210896_s_at | ASPH | aspartate beta-hydroxylase | 5.7 |
| 217678_at | SLC7A11 | solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 | 5.1 |
| 204058_at | ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 4.9 |
| 202923_s_at | GCLC | glutamate-cysteine ligase, catalytic subunit | 4.4 |
| 201468_s_at | NQO1 | NAD(P)H dehydrogenase, quinone 1 | 4.4 |
| 210519_s_at | NQO1 | NAD(P)H dehydrogenase, quinone 1 | 4.4 |
| 209641_s_at | ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 4.3 |
| 209160_at | AKR1C3 | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) | 4.2 |
| 207469_s_at | PIR | pirin (iron-binding nuclear protein) | 4.2 |
| 209135_at | ASPH | aspartate beta-hydroxylase | 4.1 |
| 202922_at | GCLC | glutamate-cysteine ligase, catalytic subunit | 3.8 |
| 209699_x_at | AKR1C2 | aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) | 3.7 |
| 208415_x_at | ING1 | inhibitor of growth family, member 1 | 3.6 |
| 216594_x_at | AKR1C1 | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) | 3.5 |
| 204151_x_at | AKR1C1 | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) | 3.4 |
| 213112_s_at | SQSTM1 | sequestosome 1 | 3.4 |
| 211653_x_at | AKR1C2 | aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) | 3.4 |
| 221432_s_at | SLC25A28 | solute carrier family 25, member 28 | 3.3 |
| 203925_at | GCLM | glutamate-cysteine ligase, modifier subunit | 3.3 |
| 202435_s_at | CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 3.2 |
| 218446_s_at | FAM18B | family with sequence similarity 18, member B | 3.2 |
| 202436_s_at | CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 3.2 |
| 212153_at | POGZ | pogo transposable element with ZNF domain | 3.2 |
| 209121_x_at | NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 3.1 |
| 204341_at | TRIM16 | tripartite motif-containing 16 | 3.1 |
| 212151_at | PBX1 | pre-B-cell leukemia transcription factor 1 | 3.0 |
| 212767_at | MTG1 | mitochondrial GTPase 1 homolog (S. cerevisiae) | 3.0 |
| 202017_at | EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 3.0 |
| 205623_at | ALDH3A1 | aldehyde dehydrogenase 3 family, memberA1 | 2.9 |
| 209380_s_at | ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.9 |
| 204169_at | IMPDH1 | IMP (inosine monophosphate) dehydrogenase 1 | 2.9 |
| 201266_at | TXNRD1 | thioredoxin reductase 1 | 2.8 |
| 219034_at | PARP16 | poly (ADP-ribose) polymerase family, member 16 | 2.8 |
| 203222_s_at | TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 2.8 |
| 208791_at | CLU | clusterin | 2.8 |
| 39249_at | AQP3 | aquaporin 3 (Gill blood group) | 2.7 |
| 217626_at | AKR1C1 | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) | 2.7 |
| 221867_at | LOC9683 | Nedd4 binding protein 1 | 2.7 |
| 203366_at | POLG | polymerase (DNA directed), gamma | 2.6 |
| 214696_at | LOC84981 | hypothetical protein MGC14376 | 2.6 |
| 202820_at | AHR | aryl hydrocarbon receptor | 2.6 |
| 202210_x_at | GSK3A | glycogen synthase kinase 3 alpha | 2.6 |
| 218639_s_at | ZXDC | ZXD family zinc finger C | 2.6 |
| 205808_at | ASPH | aspartate beta-hydroxylase | 2.6 |
| 211607_x_at | EGFR | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2.6 |
| 219475_at | LOC29948 | pregnancy-induced growth inhibitor | 2.6 |
| 214196_s_at | TPP1 | tripeptidyl peptidase I | 2.6 |
| 203811_s_at | DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 2.5 |
| 209109_s_at | TSPAN6 | tetraspanin 6 | 2.5 |
| 209592_s_at | WDR68 | WD repeat domain 68 | 2.5 |
| 206515_at | CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 2.5 |
| 209005_at | FBXL5 | F-box and leucine-rich repeat protein 5 | 2.5 |
| 218326_s_at | LGR4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 2.5 |
| 202884_s_at | PPP2R1B | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | 2.4 |
| 219534_x_at | CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 2.4 |
| 206829_x_at | ZNF430 | zinc finger protein 430 | 2.4 |
| 212979_s_at | LOC9747 | KIAA0738 gene product | 2.4 |
| 215954_s_at | C19orf29 | chromosome 19 open reading frame 29 | 2.4 |
| 216237_s_at | MCM5 | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 2.4 |