TABLE 3.

ASSOCIATIONS BETWEEN THE USE OF HOUSEHOLD CLEANING SPRAYS AT LEAST WEEKLY AND THE INCIDENCE OF ASTHMA, STRATIFIED BY SEX, CURRENT SMOKING, AND ATOPY AT FOLLOW-UP

	No.	Spray Use (%)	Current Asthma* RR (95% CI)	Current Wheeze† RR (95% CI)	Physician-diagnosed Asthma‡ HR (95% CI)
Women	2,407	48	1.45 (1.04−2.02)	1.35 (0.97−1.88)	1.51 (0.87−2.64)
Men	1,096	30	1.76 (0.99−3.15)	1.38 (0.89−2.14)	0.61 (0.16−2.25)
Ever-smokers	1,860	43	1.35 (0.91−1.99)	1.32 (0.97−1.81)	1.29 (0.67−2.50)
Never-smokers	1,608	41	1.61 (1.05−2.47)	1.51 (0.93−2.46)	1.42 (0.68−2.97)
Atopics§	716	42	1.30 (0.80−2.13)	1.39 (0.88−2.20)	1.33 (0.56−3.12)
Nonatopics	2,262	43	1.33 (0.90−1.95)	1.36 (0.96−1.94)	1.12 (0.58−2.16)

For definition of abbreviations, see Table 2.

RRs*^† or HRs^‡ with 95% CIs from log-binomial*^† or Cox proportional hazards^‡ regression models, adjusted for sex, age, smoking status, cleaning job, and study center. The reference category consisted of participants that used sprays never or less than once a week.

^*Attack of asthma and/or nocturnal attack of shortness of breath in the last 12 months and/or current asthma medication.

^†Wheezing or whistling in the chest when not having a cold in the last 12 months.

^‡Diagnosis of asthma with recorded year of onset.

^§Specific IgE to at least one of four common aeroallergens.