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Increased APE activity after HOCl treatment. HeLa cells were treated with HOCl (130 nM), and APE-1 levels in mock- and HOCl-treated lysates were assessed by Western blot analysis (Inset). Aliquots of 10 μg total protein of nontreated (a) and HOCl-treated (b) cells were used. APE activity was assayed in extracts of treated (•) and untreated control (○) cells.
