Figure 3.

Regions of sequence identity between CEH-22 and Nkx2.5. (A) Schematic diagram of CEH-22 and Nkx2.5 indicating the positions of conserved sequences (numbered according to the predicted protein sequence). The overall levels of amino acid sequence identity are reported for the homeodomains and for the portions of the proteins outside the homeodomains. (B) Sequence alignments between conserved regions of CEH-22 and Nkx2.5. Amino acid identities are indicated by a colon (:) and similarities by a period (.); numbering indicates the location of these sequences within the primary amino acid sequence. A portion of the NK2-specific domain consensus reported in ref. 1 is shown with residues present in both CEH-22 and Nkx2.5 underlined.