Table 1.
Requirement of the PR in the stroma and/or the epithelium for alveolar development in mammary transplants analyzed post partum
Transplant | No. samples with alveolar growth/no. successful transplants |
---|---|
Mammary glands in toto | |
Stroma PR+/+/epithelium PR+/+ | 8/8 |
Stroma PR−/−/epithelium PR−/− | 0/8 |
Fat pad injected with PR+/+ROSA26 epithelium cells | |
Stroma PR+/+/injected epithelium PR+/+ | 6/6 |
Stroma PR+/−/injected epithelium PR+/+ | 8/8 |
Stroma PR−/−/injected epithelium PR+/+ | 6/6 |
Epithelium | |
Stroma (host) PR+/+/epithelial transplant PR+/+ | 13/13 |
Stroma (host) PR+/+/epithelial transplant PR−/− | 0/13 |