Table 4.
Association between diabetes and serum concentrations of total PCBs, PCB-153, PCB-74, mirex, HCB, and DDE, adjusted for certain diabetes risk factors.a
| Wet-weight measurement
|
Lipid-standardized measurement
|
|||
|---|---|---|---|---|
| Analyte | Unadjusted for the other analytesb OR (95%CI) | Concurrent adjustment for the other analytesb OR (95%CI) | Unadjusted for the other analytesb OR (95%CI) | Concurrent adjustment for the other analytesb OR (95%CI) |
| Total PCBs (ppb) | ||||
| Medium tertile | 2.2 (0.8–5.9) | 1.8 (0.6–5.5) | 1.8 (0.8–4.3) | 1.5 (0.6–4.0) |
| Highest tertile | 3.9 (1.5–10.6) | 2.8 (0.7–10.8) | 3.2 (1.4–7.5) | 2.6 (0.8–8.1) |
| Mirex (ppb) | ||||
| Medium tertile | 1.2 (0.5–2.7) | 0.7 (0.3–1.7) | 0.8 (0.3–2.0) | 0.6 (0.3–1.4) |
| Highest tertile | 1.0 (0.4–2.2) | 0.3 (0.1–0.8) | 0.9 (0.4–2.2) | 0.3 (0.1–0.9) |
| DDE (ppb) | ||||
| Medium tertile | 1.8 (0.6–5.2) | 1.4 (0.4–4.3) | 2.4 (0.7–8.3) | 1.6 (0.5–4.8) |
| Highest tertile | 6.4 (2.2–18.4) | 2.6 (0.8–8.8) | 6.2 (1.8–21.9) | 2.4 (0.7–8.3) |
| HCB (ppb) | ||||
| Medium tertile | 0.9 (0.3–2.7) | 0.9 (0.3–2.6) | 2.7 (0.9–8.0) | 2.5 (0.9–6.8) |
| Highest tertile | 6.2 (2.3–16.9) | 4.5 (1.4–14.3) | 6.8 (2.3–20.3) | 4.8 (1.7–13.9) |
| PCB-153 (ppb) | ||||
| Medium tertile | 1.0 (0.4–2.5) | 0.8 (0.2–2.4) | 1.0 (0.4–2.3) | 0.6 (0.2–1.6) |
| Highest tertile | 3.2 (1.3–8.2) | 3.0 (0.7–12.8) | 2.4 (1.0–5.6) | 1.4 (0.4–4.8) |
| PCB-74 (ppb) | ||||
| Medium tertile | 1.3 (0.4–3.7) | 1.3 (0.4–4.4) | 1.3 (0.3–4.7) | 0.9 (0.3–3.0) |
| Highest tertile | 4.9 (1.7–13.7) | 3.6 (1.0–13.4) | 4.5 (1.3–15.6) | 2.9 (0.8–10.5) |
CI, confidence interval.
a
All ORs were adjusted for sex, age category, BMI category, and lifetime smoking status; in addition, wet-weight values were adjusted for estimated total lipid concentration.
b
Other analytes included serum concentrations of DDE, HCB, and mirex for total PCBs, PCB-153, and PCB-74; total PCBs, DDE, and HCB for mirex; total PCBs, mirex, and HCB for DDE; and total PCBs, mirex, and DDE for HCB.