Figure 4.

Total sleep deprivation from 5–10 h after training does not impair contextual or cued fear conditioning. (A) Sleep-deprived mice (n = 20) were not significantly different in levels of freezing in response to the shocked context than nonsleep-deprived mice (n = 19 per group; P > .05). Sleep-deprived mice did not differ from nonsleep-deprived mice in freezing in the altered chamber (pre CS) or in freezing in response to the cue (n = 19 per group; P > .05). (B) Specificity of freezing to the shocked context (delta context) measured by the difference in percent freezing between the shocked and altered context was not different in mice that were sleep-deprived from 5–10 h after training than in nonsleep-deprived mice (n = 19 per group; P > .05). Cue-specific freezing (delta cue) is not altered by sleep deprivation from 5–10 h after training (n = 19 per group; P > .05).