Figure 5.

Enrichment also reduced the age-related memory impairment of females during the spatial probe trial. Similar to males, this improvement was particularly evident in the proximity measure (B), in which middle-aged social control females swam further from the platform location than adult social control females (*P < 0.05), whereas middle-aged enriched females and adult social control females did not differ. There was also a strong trend for middle-aged enriched females to spend more time in the correct quadrant than middle-aged social control females. Quadrant time (A), proximity (B), and platform crossings (C) are presented. Open bar represents adult social control females; cross-hatched bar, middle-aged social control females; closed bar, middle-aged enriched females. Each bar represents the mean ± SEM for each group.