Figure 5.
Conditioning produces enhanced excitability of identified type Ie interneurons as compared to pseudorandom controls. (A1) An example of the CS-elicited depolarization and increase in spike frequency recorded in a type Ie interneuron from a conditioned animal and a pseudorandom control (B1). (A2–A4) Excitability was assessed in the type Ie interneuron shown in (A1) from a conditioned animal with 2-sec depolarizing extrinsic current pulses of increasing intensity (0.1 nA–0.3 nA). (B2–B4) Excitability of the type Ie interneuron shown in (B1) from a pseudorandom control assessed with 2-sec depolarizing extrinsic current pulse of increasing intensity (0.1 nA–0.3 nA). (C) Group data showing the mean evoked spikes recorded in type Ie interneurons from conditioned animals (n = 10) and pseudorandom controls (n = 12) for the three different depolarizing current levels (*P<.05).