Table 1.

Characterization of LFS heterozygotes

Cell population	Passage	Cell doubling time, h	p53 genotype	Ploidy in colcemid	Class of mutation
NHF	p9	20	+/+	4n	—
SF	p9	44	+/248W	4n	Class I
O41	p17	60	+/184T	4n	Truncation
JML	I*	30	184T/184T	4n	Truncation
174	p12	21	+/175H	Polyploid	Class II
4404	p11	39	+/175H	Polyploid	Class II
9136	p18	77	+/245D	Polyploid	Class II
143A	p11	26	+/+/143A	Polyploid	Class II
175H	p8	25	+/+/175H	Polyploid	Class II
281G	p11	24	+/+/281G	Polyploid	Class II

^*Immortal.