Table 2.
Level of Kb expression on TAP1−/− dGuo-resistant thymic epithelial cells in the presence and absence of exogenously added peptides
| Peptide | Concentration, M | Thymic selection* | No. peptide-induced Kb molecules per cell |
|---|---|---|---|
| None | None | None | None |
| LSPFPFDL | 3 × 10−5 | Positive | 718 ± 428 |
| LSPFPFDL | 5 × 10−4 | Negative | 2,318 ± 1,243 |
| EQYKFYSV | 1 × 10−4 | Positive | 12,400 ± 1,500 |
| EQYKFYSV | 3 × 10−3 | Negative | 18,900 ± 4,040 |
| SIYRYYGL | 1 × 10−8 | Positive | ND |
| SIYRYYGL | 1 × 10−7 | Negative | ND |
Average numbers and standard deviations shown are based on at least three independent measurements. ND, not detectable by assay.
*
As observed in independent RTOC experiments.