Abstract
Seventy patients with Hodgkin's disease have been treated with a combination of chlorambucil, vinblastine, procarbazine and prednisolone (Ch1VPP). The complete remission rate of 75-7% compares well with that produced by other combinations. The combination is non-toxic, easily administered and can be given safely to outpatients. Its main advantage is that it is far less upsetting to patients than combinations containing nitrogen mustard.
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Selected References
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- Carbone P. P., Kaplan H. S., Musshoff K., Smithers D. W., Tubiana M. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res. 1971 Nov;31(11):1860–1861. [PubMed] [Google Scholar]
- Devita V. T., Jr, Serpick A. A., Carbone P. P. Combination chemotherapy in the treatment of advanced Hodgkin's disease. Ann Intern Med. 1970 Dec;73(6):881–895. doi: 10.7326/0003-4819-73-6-881. [DOI] [PubMed] [Google Scholar]
- LACHER M. J., DURANT J. R. COMBINED VINBLASTINE AND CHLORAMBUCIL THERAPY OF HODGKIN'S DISEASE. Ann Intern Med. 1965 Mar;62:468–476. doi: 10.7326/0003-4819-62-3-468. [DOI] [PubMed] [Google Scholar]
- McElwain T. J., Wrigley P. F., Hunter A., Crowther D., Malpas J. S., Peckham M. J., Smithers D. W., Fairley G. H. Combination chemotherapy in advanced and recurrent Hodgkin's disease. Natl Cancer Inst Monogr. 1973 May;36:395–402. [PubMed] [Google Scholar]
- Nicholson W. M., Beard M. E., Crowther D., Stansfeld A. G., Vartan C. P., Malpas J. S., Fairley G. H., Scott R. B. Combination chemotherapy in generalized Hodgkin's disease. Br Med J. 1970 Jul 4;3(5713):7–10. doi: 10.1136/bmj.3.5713.7. [DOI] [PMC free article] [PubMed] [Google Scholar]