Figure 2.
TP53 cell line mutations detected by HRM. Cell line mutant samples are in red and wild-type samples are in blue. Normalised plots are on the left and the corresponding difference plots are on the right. Panel A - T47D 580C>T mutation in exon 6. Panel B - OVCAR-3 743G>A mutation in exon 7. Panel C - MDA-MB231 839G>A, SW480 818G>A, RPMI8226 853G>A mutations in exon 8.