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The Kp between the aqueous phase and the lipid phase composed by PazePC, PoxnoPC, or lysoPC for the three drugs used in this study
| Drug | PazePC | PoxnoPC | lysoPC |
|---|---|---|---|
| CPZ | >1 × 108 | 1.70 × 106 | 7.45 × 105 |
| DOX | 1.18 × 106 | 1.92 × 106 | 5.95 × 105 |
| HPD | 4.29 × 105 | – | 3.50 × 105 |
The values were obtained after the drug-induced quenching of pyrene-labeled phospholipid analog (see Materials and Methods).
