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. Author manuscript; available in PMC: 2008 Jan 1.
Published in final edited form as: Neurosci Biobehav Rev. 2007 Jun 5;31(6):882–896. doi: 10.1016/j.neubiorev.2007.05.009

Figure 3. Locomotor patterns of dopamine transporter knockdown and wildtype littermate mice in the Behavioral Pattern Monitor.

Figure 3

Representative locomotor patterns of dopamine transporter wildtype (WT; a) and knockdown (KD; b) mice are shown. a) WT mice spend most of their time near the chamber walls and while some movement is made to explore the center, activity is concentrated in the left wall, where the mouse circles back and forth. b) In contrast to the time spent in the home corner by the WT mouse, this KD mouse displayed numerous areas of interest and exhibited more varied paths of activity. Locomotor activity (transitions), pattern (spatial d), and exploration (holepokes) data are provided, with the KD mice displaying greater activity, exploratory behavior, and straighter line movements (lower spatial d) when compared to their WT littermates.