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Trypanothione regeneration following diamide-induced oxidant stress in L. donovani promastigotes. Regeneration of T(SH)2 over time was monitored as described. Plotted values represent the percentage of T(SH)2 found in untreated control cells: wild-type (control line; ○), pTEXTcTRtdm (TR underexpressing line; •), and pTEXTcTR (TR overexpressing line; ▪).
