Table 3.
Hydrogen peroxide metabolism and toxicity to L. donovani
| Cell type | TR mU/mg | H2O2 metabolism, nmol/min/108 cells | IC50, mM |
|---|---|---|---|
| LV9 wild type | 220 | 7.2 ± 0.9 | 0.42 ± 0.08 |
| +pTEXTcTRtdm | 36 | 6.4 ± 1.0 | 0.35 ± 0.06 |
| +pTEXTcTR | 1,836 | 7.0 ± 0.6 | 0.38 ± 0.06 |
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