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Antibacterial activity of RWJ-49815 against MRSA. (A) Time kill curve of RWJ-49815 against MRSA OC2089 at one times and four times MIC. (▪) Drug-free control; (♦) RWJ-49815 one times MIC; (•) RWJ-49815 four times MIC. (B) Time kill curve RWJ-49815 against MRSA OC2878 with a control drug, levofloxacin. The dotted line indicates the limit of detection of bacterial counts. (▪) Drug-free control; (♦) Levofloxacin two times MIC; (•) RWJ-49815 two times MIC.
