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. 1998 Apr 28;95(9):5317–5322. doi: 10.1073/pnas.95.9.5317

Figure 6.

Figure 6

(A) Concentration-dependent effect of RWJ-49815 on the growth rate of E. coli strain OC3047 harboring the Taz-1 two-component system and reporter gene. Concentrations of RWJ-49815: (○) μM; (⋄) 1 μM; (□) 2 μM; (x) 4 μM; (+) 8 μM; (•) 16 μM; (♦) 32 μM; (▪) 64 μM; and (▾) 128 μM. Bacteria incubated with concentrations of RWJ-49815 up to 4 μM had mean generation times of 56 min that were indistinguishable from the no-drug control. Bacteria incubated with 8 μM RWJ-49815 had a doubling time of 67 min. (B) Effect of RWJ-49815 on the Taz-1 induction of β-galactosidase.