Table 1.
Demographic characteristics and densities of GAT-1-immunoreactive axon cartridges in the three subject groups
| Subject group
|
Analysis | |||
|---|---|---|---|---|
| Control | Schizophrenic | Psychiatric | ||
| Male/female ratio | 10:5 | 10:5 | 10:5 | P = NS |
| Age, years | 53.9 ± 13.8 | 53.6 ± 13.0 | 53.7 ± 12.4 | P = NS |
| Postmortem interval, h | 11.3 ± 5.4 | 11.7 ± 5.6 | 11.6 ± 5.2 | P = NS |
| Age at onset of illness, years* | NA | 26.5 ± 7.2 | 34.3 ± 15.4 | P = NS |
| Duration of illness, years* | NA | 26.7 ± 12.4 | 16.9 ± 12.5 | P = 0.097 |
| % suicide | 0.0 | 13.3 | 40.0 | P = 0.014 |
| % out-of-hospital deaths | 93.3 | 80.0 | 80.0 | P = NS |
| Tissue storage, months | 52.3 ± 18.3 | 54.9 ± 22.4 | 44.4 ± 25.7 | P = NS |
| Cartridge density, mm−2 | ||||
| Area 9 | 37.9 ± 17.0 | 20.9 ± 15.3 | 36.2 ± 9.3 | F2, 39 = 9.24, P = 0.0005 |
| Area 46 | 43.8 ± 16.0 | 26.0 ± 14.3 | 41.3 ± 12.2 | F2, 39 = 8.35, P = 0.001 |
All values are the mean ± SD. NS, not significant; NA, not applicable.
*
Because the available data were insufficient to determine the age of onset of three psychiatric subjects, the schizophrenic and psychiatric subjects from these triads (patients 2, 5, and 6) were not included in these analyses.