Table 2.
Inhibition of E2F1–DNA complex formation by DNA-binding drugs
Drug | Relative activity |
---|---|
Dm | 1.0 |
MGT-1 | 4.6 |
MGT-5a | 6.3 |
MGT-6a | 4470 |
MGT-6b | 2714 |
MGT-7 | 48.7 |
MGT-8 | 2375 |
Relative activity was normalized by comparing the IC50 of individual drugs to that of Dm.