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. 1997 Apr 1;94(7):2885–2890. doi: 10.1073/pnas.94.7.2885

Figure 5.

Figure 5

HRE5 participates in synergistic induction by ligand activated GR. (A) Influence of mutations in the HRE5 site on the activity of the MMTV promoter. The mutation is described in Materials and Methods. (B) Schematic array of sites: distance between HRE5 and the NFI site. (C) Hypothetical model of GR and NFI bound to their cognate sites on the surface of a nucleosome. A GR (bold) bound to HRE5 would be close to the DNA-bound NFI. The model and the positions of the cis elements are not drawn to scale.