Figure 7.

(A) Schematic representation of a two-step TP–DNA replication process. Time required for the initiation step of TP-primed DNA replication is indicated as τ_i. (TP–DNA)_i stands for an initiated complex (only one initiation event is considered, for simplicity). Time required for an initiated complex to achieve full-length DNA elongation is indicated as τ_e. See Discussion for more details. (B) Theoretical dependence between duplication time and DNA length. τ_i and τ_e represent the times required for TP-primed initiation and full-length DNA elongation, respectively. L and V_e stand for the length of the replicating molecule and the velocity of DNA polymerase, respectively. See Discussion for more details.