Figure 3.

Factor D activity of normal serum and partially or completely factor D–deficient serum. (a) Depiction of the factor D activity of the various sera diluted with different amounts of factor D–depleted serum (dilutions from 1:50 to 1:4). Diamonds, normal serum; squares, propositus V:7; triangles, normal family member III:4; circles, mother of the propositus IV:8; asterisks, brother V:9 of the propositus. (b) The restoration of factor D activity in the serum of the propositus by addition of different amounts of purified factor D. The results shown in these figures are representative of three independent experiments.