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. Author manuscript; available in PMC: 2008 Jul 20.
Published in final edited form as: Biochem Biophys Res Commun. 2007 May 22;359(1):94–101. doi: 10.1016/j.bbrc.2007.05.072

Fig. 4.

Fig. 4

Assay of tobramycin beacon aptamer activity. Data are plotted as “Fraction of maximum fluorescence” vs. concentration of ligand (tobramycin or paromomycin). Maximum fluorescence was measured in the presence of a 100-fold molar excess of a complementary DNA oligonucleotide. Error bars are standard deviations (number of replicate measurements ranged from 3 to 12). (A) Effect of tobramycin on the fluorescence of BA14–1 and BA6–8 (B) Effect of tobramycin on the fluorescence of BA14–2. The data for BA14–1 and BA14–2 were fit to hyperbolic binding curves. The data for BA6–8 was fit to a line.