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. Author manuscript; available in PMC: 2008 Jul 1.
Published in final edited form as: Exp Eye Res. 2007 Mar 31;85(1):113–122. doi: 10.1016/j.exer.2007.03.007

Figure 6. PKCγ C1B mutations cause N/N1003A cells to be more susceptible to H2O2-induced apoptosis (caspase-3 activity assay): prevention using a gap junction inhibitor.

Figure 6

Cells were treated with 100 μM H2O2 for different time periods. Cell apoptosis was determined by caspase-3 activity assay. In addition, cells were pre-incubated with 200 μM AGA for 30 min followed by addition of 100 μM H2O2 for additional 3 h and caspase-3 activation was analyzed (AGA+H2O2 (3h) columns) . * indicates significant changes compared to levels in control cells with overexpression of wild type PKCγ.