. 1997 Apr 1;94(7):3010–3015. doi: 10.1073/pnas.94.7.3010

Table 1.

Effects of cAMP on NHE3 activity in PS120/NHE3V fibroblasts transfected with NHERF or E3KARP

Cell lines	Treatment	V_max, μM/sec	K′(H_i⁺), μM	n_app
PS120/NHE3V/NHERF	Control	2,206 ± 223	0.18 ± 0.07	1.8
	+ 8-Br-cAMP	1,579 ± 183^*	0.15 ± 0.07	1.8
PS120/NHE3V	Control	2,401 ± 176	0.12 ± 0.05	1.7
	+ 8-Br-cAMP	2,283 ± 170	0.12 ± 0.04	1.7
PS120/NHE3V/GST-E3KARP	Control	1,382 ± 180	0.14 ± 0.08	1.8
	+ 8-Br-cAMP	998 ± 164^*	0.17 ± 0.07	2.1
PS120/NHE3V/GST	Control	1,796 ± 124	0.11 ± 0.04	1.8
	+ 8-Br-cAMP	1,612 ± 172	0.10 ± 0.05	2.0

Data are presented as means ± SE. n ≥ 4 for all experiments. Na⁺/H⁺ exchange activity measurements shown in Fig. 3 are tabulated.

P < 0.05 vs. control.