Figure 5.

Localization of Ro protein in skin by immunogold labeling with antiserum C. Isolated gold particles (10 nm) are scattered through the cell, including the cluster of interchromatin granules (ig) but excluding the desmosomes (d). In addition, clusters of gold particles (10 nm) are present within the nucleoplasm (1), at the nuclear border (2), and in the juxtanuclear cytoplasm (3) in association with electron-opaque bodies. Formaldehyde fixation was 4%. Image produced by uranyl acetate staining. (Bar = 0.5 μm.)