Table 1.
5-HTTLPR genotype frequencies by treatment and abstinence at 12-week and 24-week follow-ups.
5-HTTLPR Genotype
|
|||||||||
---|---|---|---|---|---|---|---|---|---|
SS
|
SL
|
LL
|
|||||||
Active (n=72) | Placebo (n=59) | Combined (n=131) | Active (n=173) | Placebo (n=180) | Combined (n=353) | Active (n=125) | Placebo (n=132) | Combined (n=257) | |
12-Week | |||||||||
Succeeded | 18 (25%) | 7 (12%) | 25 (19%) | 33 (19%) | 18 (10%) | 51 (14%) | 24 (19%) | 18 (14%) | 42 (16%) |
Failed | 54 (75%) | 52 (88%) | 106 (81%) | 140 (81%) | 162 (90%) | 302 (86%) | 101 (81%) | 114 (86%) | 215 (84%) |
24-Week | |||||||||
Succeeded | 12 (17%) | 4 (7%) | 16 (12%) | 22 (13%) | 12 (7%) | 34 (10%) | 23 (18%) | 18 (14%) | 41 (16%) |
Failed | 60 (83%) | 55 (93%) | 115 (88%) | 151 (87%) | 168 (93%) | 319 (90%) | 102 (82%) | 114 (86%) | 216 (84%) |
Note. All values are numbers of subjects with percentages.