TABLE 3.
Fracture risk following hysterectomy in 1965-2002 among 9258 Olmsted County, Minnesota, women compared to 9258 age-matched community controls, by indication for surgery.
| Indication (n) | Any fracture HR (95% CI)a | Osteoporotic fracture HR (95% CI)a |
|---|---|---|
| Cancer of reproductive tract (949) | 1.21 (0.97-1.51) | 1.03 (0.74-1.44) |
| Debulking of urinary or GI cancer (126) | 1.82 (1.01-3.29) | 2.00 (0.86-4.67) |
| Pre-cancerous conditions (2173) | 1.10 (0.96-1.26) | 0.97 (0.77-1.21) |
| Uterine leiomyomata (2607) | 1.12 (0.98-1.27) | 0.99 (0.81-1.22) |
| Endometriosis (705) | 1.46 (1.11-1.92) | 1.38 (0.81-2.33) |
| Uterine/vaginal prolapse (1139) | 1.28 (1.07-1.54) | 1.33 (1.01-1.74) |
| Menstrual disorders (1117) | 1.50 (1.21-1.87) | 1.23 (0.79-1.92) |
| Menopausal disorders (79) | 0.93 (0.44-1.98) | 0.57 (0.17-1.95) |
| Inflammatory diseases of pelvis (270) | 1.18 (0.79-1.77) | 1.44 (0.76-2.72) |
| Other indications (93) | 1.29 (0.48-3.45) | 1.50 (0.25-8.98) |
a
Hazard ratio from a stratified hazards model.