Table 3.

Summary of cNSC cochlear localization and protein expression. This table lists those markers that were expressed in transplanted cNSCs. In most cases, cNSCs had upregulated those markers that are expressed by endogenous cells of the microenvironment.

cNSC Localization	Mouse		Guinea Pig
cNSC Localization	Expressed	Not Expressed	Expressed	Not Expressed
Inner hair cell	myosin 7a⁺	GFAP^-	No Observed Localization
Outer hair cell	No Observed Localization		calbindin^+/-, myosin 7a⁺, oncomodulin⁺	NF200^-
Pillar cell	βIII tubulin⁺	p75^-, GFAP^-	†	calbindin^-, oncomodulin^-
Deiters' cell	GFAP⁺	βIII tubulin^-, myosin 7a^-, NF 200^-	GFAP⁺	myosin 7a^-, S100β^-
Inner phalangeal cell	GFAP⁺	myosin 7a^-, NF 200^-	GFAP⁺	calbindin^-, myosin 6^-, oncomodulin^-, S100β^-
Spiral ganglion neuron	NF 200⁺, βIII tubulin⁺, *myosin 7a*⁺,	S100β^-, GFAP^-	βIII tubulin⁺, NF 200⁺, NF M⁺	calbindin^-, oncomodulin^-, S100β^-
Satellite cell	MAP-2⁺, S100β⁺	NF 200^-	GFAP⁺, S100β⁺	βIII tubulin^-, myosin 7a, NF 200^-, NF M^-, oncomodulin^-
Schwann cell (oss. spiral lamina.)	βIII tubulin⁺	NF 200^-, GFAP^-	S100β⁺, GFAP⁺	calbindin^-, NF68^-, NF200^-, myosin 6^-
Schwann cell (VIII^th Nerve Trunk)	No Observed Localization		S100β⁺	myosin 7a^-, NF200^-
Spiral limbus (Interdental cell)	βIII tubulin⁺ *myosin 7a*⁺, S100β⁺	GFAP^-	S100β⁺	NF200^-, oncomodulin^-
Spiral ligament	*myosin 7a*⁺, S100β⁺	GFAP^-	S100β⁺	NF68^-, NF200^-
Bony labyrinth	No Observed Localization		†	myosin 7a^-, NF200^-, NF68^-, S100β^-

Key: (+) = immunohistochemistry positive; (-) = immunohistochemistry negative; (+/-) = in sections with positive calbindin labeling to endogenous cells, stem cells exhibited variable calbindin expression. Bold = immunolabeling not expected in endogenous tissue. (†)= could not determine expression due to lack of antibodies appropriate for paraffin sections