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. Author manuscript; available in PMC: 2007 Nov 9.
Published in final edited form as: Neuron. 2006 Nov 9;52(3):511–524. doi: 10.1016/j.neuron.2006.09.014

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Stimuli Generating ≤ ∼2.5 Rh*/Rod/Sec Elicit Signals in RGCs via the Rod Bipolar Pathway. A, Schematic of the retina. The rod bipolar pathway is highlighted in gray. AII = AII Amacrine Cell; RBC = Rod Bipolar Cell B1, Cell-attached recording of spikes generated in an Off transient cell by light stimuli producing ∼2.5 and ∼12.5 Rh*/Rod/Sec in the absence (Con) and presence of the mGluR6 agonist L-APB (10 μM). B2, Ratio of the number of spikes in the presence and absence of APB. C1, Whole cell voltage clamp (Vm= −70 mV) recording of the excitatory postsynaptic current (EPSC) in an Off transient cell evoked by light stimuli producing ∼2.5 and ∼12.5 Rh*/Rod/Sec under control conditions (Con) and in the presence of APB C2, Ratio of synaptic current variance in the presence and absence of APB.