Table 1.

HFH-4 consensus DNA-binding sequence

G	9	—	42	4	89	—	—	—	94	—	—	—	4
A	51	47	19	13	11	2	—	—	6	—	4	4	87
T	21	53	38	68	—	98	100	100	—	94	96	96	9
C	19	—	—	15	—	—	—	—	—	6	—	—	—
Consensus	A	A	T	T	G	T	T	T	G	T	T	T	A
	t	T	G
	c		a
Position	1	2	3	4	5	6	7	8	9	10	11	12	13

The HFH-4 DNA binding-consensus sequence is compiled from 47 high-affinity HFH-4 binding sites isolated by in vitro binding site selection using recombinant HFH-4 protein as described (24). Shown is the percent nucleotide occurrence for each nucleotide position in the HFH-4 binding site. Uppercase letters indicate nucleotides that are highly represented in DNA sites and lowercase letters indicate nucleotides that are represented half as frequently. The HFH-4 DNA binding-core sequence is indicated by the underlined nucleotides.